Barely Significant
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Synergistic Effects of Compound Dendrobium Candidum and Antihypertensive Medications on Refractory Hypertension in Spontaneously Hypertensive Rats.

Cardiol Res Pract · 2026 · PMC12977149 · PMID 41821639

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a decreasing trendno p-value reported
Furthermore, the IAT + CDC group showed a decreasing trend in the expression levels of the two proteins in comparison with the IAT group, but the difference was not statistically significant (Figures 4(a) , 4(b) , and 4(c) ; details provided in Supporting Table 7 ). 3.1.7.

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In comparison with the model group, both the IA and IAT groups exhibited a compensatory increase in the relative mRNA expression levels of AT 1 R and AT 2 R following antihypertensive treatment; however, this increase did not reach statistical significance.

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an increasing trendno p-value reported
In comparison with the model group, the CDC, IA + CDC, and IAT + CDC groups showed an increasing trend in the relative mRNA expression level of ISR.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.