Upregulation of PLAU in granulosa cells disrupts steroid hormone synthesis and promotes apoptosis by activating NF-κB signaling pathway in PCOS.

J Ovarian Res · 2025 · PMC12977547 · PMID 41462288

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6 e, PLAU was strongly expressed in GCs, whereas it was weakly expressed in oocytes and pericytes within mouse ovaries and showed a trend toward increased expression in the PCOS group than the control group.

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