An Rv1471-expressing chimpanzee adenovirus vaccine confers protection against tuberculosis by inducing alveolar macrophage trained immunity and polyfunctional T-cell responses.

Emerg Microbes Infect · 2026 · PMC12978187 · PMID 41734270

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did not reach statistical significanceno p-value reported

Although a reduction in inflammatory infiltration was observed, it did not reach statistical significance versus the BCG-primed group ( Figure 6 G-H).

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