Mitochondrial Pyruvate Metabolism Controls Alveolar Stem Cell Fate and Inflammatory Balance.

Inflammation · 2026 · PMC12979318 · PMID 41776090

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an increasing trendno p-value reported

did not reach statistical significanceno p-value reported

Expression of the macrophage-associated chemokine Ccl2 was increased, while Ccl3 showed an increasing trend that did not reach statistical significance, and the corresponding receptor Ccr2 was reduced in Mpc2 CKO lungs (Figure S1 B).

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a decreasing trendno p-value reported

In addition, Pdpn expression was significantly reduced in lung tissues from Mpc2 CKO mice, whereas Sftpc expression showed a decreasing trend but did not reach statistical significance (Fig. 7 E).

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