HLA class I expression shapes the tumor immune microenvironment and influences prognosis in prostate cancer.

Prostate Cancer Prostatic Dis · 2026 · PMC12980528 · PMID 41139148

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In the Caucasian cohort, OS patterns were similar to the overall cohort, whereas the African cohort showed a trend toward improved survival with higher HLA expression, particularly in the HLA-A allele group, opposite to the overall trend (Supplementary Fig. 4A ).

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