Functional validation of the novel KIF5A p.R17Q VUS reveals defective axonal transport in iPSC-motoneurons from a SPG10 patient.

Front Genet · 2026 · PMC12981723 · PMID 41836058

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showed a trendno p-value reported

Our results showed a trend towards a reduced velocity in mutant p.R17Q iPSC-MNs compared to the WT cells ( Figure 4b ).

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