Impaired PIEZO1 function drives uterine hypercontractility in adenomyosis-associated dysmenorrhea.

Hum Reprod Open · 2026 · PMC12981915 · PMID 41836349

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.2200

boldest claim

The sentences

highly significantP -values ≤ 5.0 × 10 −6actually significant

These correlations were still highly significant within the AM group (all 3 r ’s ≥ 0.55, all 3 P -values ≤ 5.0 × 10 −6 ).

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did not reach statistical significanceP = 0.22not close (p > 0.1)

The expression levels of iNOS in SMCs derived from the ipsilateral myometrium were slightly higher than those of control SMCs but the difference did not reach statistical significance ( P = 0.22; Fig. 3A ).

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