PDE1B and PDE10A as novel targets for schizophrenia: from molecular design and synthesis to therapeutic promise.

Front Pharmacol · 2025 · PMC12982385 · PMID 41835457

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did not reach statistical significanceno p-value reported

Secondary endpoints, including PANSS subscales, BNSS, and CGI scores, showed nominal improvements but did not reach statistical significance.

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