Transvaginal ovarian drilling prior to a second IVF cycle may improve the rate of euploidy in patients with polycystic ovarian syndrome when compared to controls.

Furthermore, there was a highly significant decrease in both the number and percentage of aneuploid embryos with TVOD as compared to the controls, + 0.47 ± 1.8 to − 1.0 ± 2.8 ( p = 0.01) in aneuploid yield and − 8.5 ± 43% to − 48.9 ± 43% ( p < 0.001) in percent aneuploidy, as shown in Table 4 .

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The association between TVOD and change in euploid embryo yield trended towards a greater increase from first to second cycle when compared to controls, but did not reach statistical significance as shown in Table 5 .

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