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Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.

Trials · 2026 · PMC12983611 · PMID 41656269

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The magnitude of improvement in the IP arms was approximately twofold higher than that observed in the placebo group, and the between-group differences were statistically significant ( p < 0.0001) (Table 6 ). Mental alertness At day 60, both investigational product (IP) arms showed a numerically greater reduction in mean Mental Alertness Scale scores compared with placebo, suggesting an improvement in mental alertness; however, these differences did not reach statistical significance (Table 7 ).

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