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Effectiveness of a web-based preventive postpartum depression programme in pregnancy, with/without telephone support: a randomised control trial.

BMJ Open · 2026 · PMC12983831 · PMID 41813052

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22 The web-based Mothers & Babies intervention was associated with reduced depressive symptoms during post partum; however, results of the time-to-event analysis, where the event was a depressive episode as defined by EPDS≥10 (cut-off revised according to the trial population), did not reach statistical significance (HR=0.598; 95% CI 0.339 to 1.022). 22 Several other web-based prenatal CBT-based interventions for depression have been studied. 37 In a systematic review, Savoia et al reported on the effectiveness of 18 prenatal web-based interventions for postpartum depression, of which 7 were based on classical

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