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Clinical and Molecular Diagnostic Profiling of Vaginitis Using Multiplex Real-Time PCR: A Multicenter Study.

Diagnostics (Basel) · 2026 · PMC12984344 · PMID 41828059

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Although the association with ≥3 symptoms did not reach statistical significance in this cohort, the overall trend supports a cumulative symptom model rather than a linear symptom–pathogen relationship, which is consistent with prior observations in mixed vaginitis and polymicrobial infections [ 24 , 25 , 33 ].

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