Barely Significant
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Atherogenic Lipid Indices in Colorectal Cancer: Metabolic Associations and Survival Outcomes.

Diagnostics (Basel) · 2026 · PMC12984757 · PMID 41828085

Europe PMCDOI
2
hedged sentences
0.0490
closest p · 1.0× alpha
0.0490
boldest claim

The sentences

borderline significantp = 0.049actually significant
The TyG index showed a borderline significant column effect (F(3,102) = 2.712, p = 0.049), indicating increasing IR from early to intermediate stages, with partial attenuation in stage IV.

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did not reach statistical significanceno p-value reported
Even though median or mean values tended to increase from stages I to III for indices such as AIP, TG/HDL, and TyG, these trends did not reach statistical significance, likely due to a smaller sample size, wide inter-individual variability, and strong confounding by diabetes-related metabolic factors.

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