Impact of Peri-Immunotherapy Antibiotic Exposure on Survival Outcomes in Metastatic Renal Cell Carcinoma: A Real-World IMDC Risk-Stratified Analysis.

J Clin Med · 2026 · PMC12985464 · PMID 41827267

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

Although the difference in ORR between antibiotic-exposed and non-exposed patients did not reach statistical significance (18.4% vs. 31.6%, p = 0.09), the absolute difference of over 13% may still be clinically meaningful.

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