Niacin Mitigates Cyclophosphamide-Induced Immunosuppression by Maintaining Intestinal Homeostasis and Regulating the HCAR2/NLRP3 and PTGS2/PGE2 Signaling Pathways.

Effect of Niacin on Alpha Diversity Analysis Relative to the CTX group, the HNA group showed a trend toward higher alpha diversity, as measured by the Chao1, Ace, Shannon, and Simpson indices ( Figure 9 A–D; p < 0.05).

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