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Volumetric MRI-based response assessment and prognostic value in newly diagnosed glioblastoma: RANO 2.0 versus mRANO versus RANO.

Neurooncol Adv · 2026 · PMC12986764 · PMID 41835953

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The authors found that using the postradiotherapy scan resulted in a stronger correlation between PFS and OS, although the difference did not reach statistical significance. 15 In line with their general observation, we also found that using postradiotherapy MRI as baseline resulted in a stronger correlation between PFS and OS, indicating that this timepoint provides a more reliable reference for assessing treatment response and disease progression. 15 Another factor

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