Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT).

Environ Mol Mutagen · 2025 · PMC12988043 · PMID 38828778

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a significant trendno p-value reported

This analysis may demonstrate a significant increase in MF over the concurrent control, a significant trend of increasing MF with increasing dose, and/or a MF in treated cultures/animals increased above historical control levels (OECD, 2016b , 2022a , 2022b ).

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