The significance level used was α = 0.05 and results were considered significantly different when p < 0.05 (*), very significant at p < 0.01 (**), and highly significant at p < 0.001 (***) (5) t = X ̄ 1 − X ̄ 2 s 1 2 n 1 + s 2 2 n 2 d f = s 1 2 n 1 + s 2 2 n 2 2 s 1 2 n 1 2 n 1 − 1 + s 2 2 n 2 2 n 2 − 1 Cohen's d was used to assess differences between groups in cases where the t ‐test did not reach statistical significance, but results approached the threshold, revealing a large effect size that suggests a relevant trend (Cohen's d threshold: d (0.01) = very small, d (0.2) = small, d (0.5) = medium, d (0.8) = large, d (1.2) = very large, and d (2.0) = huge) [ 69 ].
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Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R-Functionalized Magnetic Nanoparticles to Low-Endocytic CCR9 Surface Receptors.
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