Lung Volumes in Tobacco-Exposed Individuals with Preserved Spirometry: An Overlooked Pointer of Respiratory Health?

Lung · 2026 · PMC12988985 · PMID 41832357

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did not reach statistical significanceno p-value reported

In sensitivity analyses, treating RV/TLC and TLC as both quartile-based and continuous predictors, higher TLC was significantly associated with absolute declines in FEV 1 and FVC over follow-up whereas the corresponding associations with changes in FEV 1 /FVC were weaker and did not reach statistical significance in the continuous models (Supplementary Tables 1 and 2 ).

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