highly significantP < .001
Conversely, all non‐T1c combinations demonstrated highly significant performance degradation ( P < .001), corresponding to their substantial median differences of −0.171 to −0.199.
Conversely, all non‐T1c combinations demonstrated highly significant performance degradation ( P < .001), corresponding to their substantial median differences of −0.171 to −0.199.
The baseline and T1c + T2f protocols yielded small median volume differences and non‐significant deviations from the manual ground truth (adjusted P = 1.0 for both), and T2f‐based combinations such as T2f + T2w and T2f + T1n + T2w (adjusted P = .128 for both) also did not reach statistical significance, whereas many other protocols, except T1c + T2w (adjusted P = .054), exhibited significant volumetric errors (adjusted P < .05).