The circadian clock component PER2 deficiency aggravates airway epithelial remodeling through Wnt/β-catenin signaling pathway.

Respir Res · 2026 · PMC12990575 · PMID 41668071

Europe PMC DOI

hedged sentence

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

did not reach statistical significanceP = 0.085so close (0.05 < p ≤ 0.1)

In addition, although the correlation between PER2 expression and Immunoglobulin E (IgE) levels did not reach statistical significance ( r = –0.19, P = 0.085), a consistent negative trend was observed, which has an important role in the pathophysiology of allergic asthma (Fig. 1 L-O).

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