Neoadjuvant chemoradiotherapy with or without PD-1 inhibitors in MMR-proficient non-metastatic rectal cancer: a meta-analysis of randomized controlled trials.

Front Immunol · 2026 · PMC12992012 · PMID 41853263

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did not reach statistical significanceno p-value reported

Interestingly, while the addition of PD-1 inhibitors significantly improved pCR rates, the increase in cCR did not reach statistical significance.

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