Targeting neuroinflammation: itaconate and mesaconate as therapeutic strategies against H7N7 influenza-associated CNS damage.

Front Immunol · 2026 · PMC12992265 · PMID 41853265

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did not reach statistical significanceno p-value reported

Although mesaconate-treated H7N7-infected mice exhibited a modest trend toward reduced fEPSP slope, this effect did not reach statistical significance and likely reflects subtle modulation of synaptic gain rather than a persistent disruption of basal excitatory transmission.

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