Barely Significant
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Effectiveness of ketamine/esketamine in alleviating postoperative fatigue: a systematic review.

Int J Clin Pharm · 2026 · PMC12992384 · PMID 41222605

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a decreasing trendno p-value reported
[ 19 ] observed that while ketamine showed no advantage in brief pain inventory (BPI) scores at 24 and 48 h postoperatively, patients exhibited statistically significant improvement in the “BPI least” indicator at POD 7, along with a decreasing trend in overall pain scores.

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