Differential DNA-methylation of synaptic genes in CSF and blood in schizophrenia.

Schizophrenia (Heidelb) · 2026 · PMC12993050 · PMID 41720812

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hedged sentences

0.0100

closest p · 0.2× alpha

0.0500

boldest claim

The sentences

highly significantp < 0.01actually significant

DAT In blood, comparison of mean methylation rates between Co (18.0 + /- 0.9%) and SZ (13.8 + /- 0.4%) revealed a highly significant group difference ( p < 0.01).

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did not reach statistical significancep > 0.05actually significant

In CSF, methylation levels were slightly higher in Co (9.3 + /- 2.1%) compared to the SZ group (7.4 + /- 0.6%), but this difference did not reach statistical significance ( p > 0.05).

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