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Can alternative means of phenotyping rheumatoid arthritis reduce its apparent heterogeneity? A comparison of three disease activity classifications with DAS28.

RMD Open · 2026 · PMC12993305 · PMID 41839530

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Similarly, the ‘subjective’ subset had a higher proportion of pain diagnoses (1.5% vs 0.9%, OR 1.7, 95% CI 0.8 to 3.7) and psychiatric diagnoses (3.4% vs 2.1%, OR 1.3, 95% CI 0.8 to 2.2), but the difference did not reach statistical significance.

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