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The role of hypothyroidism in the resilience against depressive episodes during covid pandemic in a cohort of old adults.

Front Psychiatry · 2026 · PMC12993762 · PMID 41853084

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People with high social rhythm dysregulation (SBRS score >mean + 1 standard deviation) one year before lockdown were more frequent among those who had suffered from Hypothyroidism and who were currently undergoing treatment compared to the control group (26.67% vs 12.8%; Fisher Exact test, p=0.432 OR = 1.70, CI 95% 0.40-7.09; see Table 3 ), but the difference did not reach statistical significance.

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