The Leu + Cur group also presented significantly attenuated the expression levels of SLC7A11 compared with Cur group in HCT116 cells (P<0.05), while the reduction observed in Caco-2 cells did not reach statistical significance (P>0.05).
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Leucovorin enhances curcumin-induced inhibition of cell viability and ferroptosis in colorectal cancer cells.
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