Succinate supplementation ameliorates musculoskeletal defects caused by PLOD3 mutations in a BCARD syndrome model.

Enrichr analysis Zebrafish genes identified in the RNA-seq analysis that showed nominally significant ( p < 0.05) expression change between WT and mgt −/− samples were converted to their human orthologues using the HUGO Gene Nomenclature Committee (HGNC) HCOP tool and the ZFIN database [ 45 ].

also in 4,806 other papers

Comparative immunoblots of lysates from primary, patient-derived fibroblasts cultured under basal conditions showed a highly significant increase in ATG5, P62, LC3-I and LC3-II, and LAMP1 (Lysosomal-associated membrane protein 1, a lysosomal marker) (Fig. 4 E; Additional file 2 : Fig.

also in 82,756 other papers