Colonic biopsy-associated microbial signatures are predictive of response to anti-TNFα biological therapy in Crohn's disease.

Front Cell Infect Microbiol · 2026 · PMC12996044 · PMID 41859469

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did not reach statistical significanceno p-value reported

While this difference did not reach statistical significance for IFX, likely reflecting the limited sample size, the concordant direction of effect across therapies reinforces M. gnavus as a key microbial feature associated with anti-TNFα response and supports the combined analysis of anti-TNFα treatments in this study.

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