Multimodal evidence chain of iron overload, inflammation, and dysfunction: an integrated predictive model of early cardiac injury in pediatric transfusion-dependent <i>β</i>-thalassemia.

Front Cardiovasc Med · 2026 · PMC12996236 · PMID 41859542

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

did not reach statistical significancep ≥ 0.05actually significant

In contrast, age ( p = 0.62), annual transfusion frequency ( p = 0.44), iron chelation regimen ( p = 0.77), and TNF-α ( p = 0.058) did not reach statistical significance ( p ≥ 0.05).

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highly significantno p-value reported

Significance levels were set at p < 0.05, with p < 0.01 indicating highly significant differences.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Multimodal evidence chain of iron overload, inflammation, and dysfunction: an integrated predictive model of early cardiac injury in pediatric transfusion-dependent &lt;i&gt;β&lt;/i&gt;-thalassemia.

The sentences

Multimodal evidence chain of iron overload, inflammation, and dysfunction: an integrated predictive model of early cardiac injury in pediatric transfusion-dependent <i>β</i>-thalassemia.