Conditional survival in glioblastoma: The evolution of prognostic factors over time.

In the multivariate landmark analysis at time points 6, 12, 18, and 24 months (Figure 5B–E ), only age at diagnosis and MGMT promoter methylation approached significance at 18 months. 4 DISCUSSION Our study provides a novel look at the analysis of clinical, surgical, and molecular factors at different time points, thereby illustrating the temporal evolution of prognostic factors in patients with glioblastoma.

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