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Alexander disease mutations differentially sensitize glial fibrillary acidic protein (GFAP) to posttranslational modifications and network disruption by oxidants.

Redox Biol · 2026 · PMC12996815 · PMID 41830670

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showed a trendno p-value reported
Chlorination at Y285 in the R239C mutant also showed a trend towards a decrease.

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