Setd1a Loss-of-function Disrupts Epigenetic Regulation of Ribosomal Genes via Altered DNA Methylation.

35 Identification of Differentially Methylated Regions Differentially methylated regions (DMRs) were defined as more than 1 consecutive DNA methylation site spaced less than 1500 base pairs apart, with a nominally significant ( P < .05) main effect of genotype, and each with the same direction of effect.

also in 4,806 other papers

We selected 3 snoRNAs annotated to highly significant DMPs and quantified their expression in the cytosolic fraction from wildtype and Setd1a +/− frontal cortex at P7 when clear changes in the methylation of these snoRNAs were observed.

also in 82,756 other papers