Barely Significant
← all excerpts

Progression patterns and clinical outcomes in patients with cutaneous squamous-cell carcinoma following anti-PD-1 therapy failure.

ESMO Open · 2026 · PMC12997212 · PMID 41819748

1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

showed a trendP = 0.08so close (0.05 < p ≤ 0.1)
No significant differences in mutation enrichment were observed between primary and secondary resistance, although TP53 showed a trend toward primary resistance ( P = 0.08), and HRAS trended toward secondary resistance ( P = 0.06).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.