Efficacy of Nebulized Pentoxifylline in a Mouse Model of Emphysema Induced by Cigarette Smoke and Aerosolized Lipopolysaccharide.

Int J Chron Obstruct Pulmon Dis · 2026 · PMC12997780 · PMID 41859016

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a numerical trendno p-value reported

A numerical trend indicated that pentoxifylline at a concentration of 22.0 mg/mL might exhibit greater efficacy; however, no statistically significant differences were observed among the various PTX doses tested.

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did not reach statistical significanceno p-value reported

Although THEO induced a reduction in TNF-α levels, this change did not reach statistical significance.

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