nominally significantp < 0.05
For region-level analyses, considering the 136 MR estimates, a Bonferroni-corrected P -value of 0.05/136 (3.676 × 10 − 4 ) was applied, while nominally significant findings were defined as p < 0.05.
For region-level analyses, considering the 136 MR estimates, a Bonferroni-corrected P -value of 0.05/136 (3.676 × 10 − 4 ) was applied, while nominally significant findings were defined as p < 0.05.