Cell type resolved MR based on brain single cell eQTLs corroborated by single cell RNA sequencing uncovers neuroimmune and vascular programs in intracerebral hemorrhage.

In two-sample Mendelian randomization with inverse-variance weighting as the primary estimator and other robust methods as comparators, we identified 524 nominally significant gene–cell type associations with ICH risk at an unadjusted P value less than 0.05.

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