However, debate persists regarding the optimal antimicrobial prophylaxis strategy in TPB: Although some reports indicate that TPB can be safely performed without antimicrobial prophylaxis, 4 , 5 , 23 , 24 Jacewicz et al 25 reported that TPB without antibiotic prophylaxis showed a slightly increased incidence of urinary tract infections, although the difference failed to reach statistical significance (0.36% vs 1.09%; p = 0.31).
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Safety of Single-Dose Oral Cefaclor Prophylaxis in Transperineal Prostate Biopsy.
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