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White matter lesions modifying endovascular therapy outcomes in large ischemic core stroke: A secondary analysis of the ANGEL-ASPECT trial.

Chin Med J (Engl) · 2026 · PMC12999128 · PMID 41641580

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Thus, although the interaction term did not reach statistical significance, the difference in the magnitude of benefit across WML subgroups suggests a clinically meaningful interaction that our study may have been underpowered to detect.

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