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The Research Domain Criteria (RDoC) domains positive valence system, negative valence system, cognitive systems, and social processes and their relationship with stress, anxiety, and depressive symptoms in a university student sample.

Front Psychiatry · 2026 · PMC12999574 · PMID 41868839

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Although the overall regression model did not reach statistical significance, a statistically significant difference in the prevalence of depressive symptoms was observed between students of the Faculty of Human Sciences and those of the Faculty of Science ( b = -2.044, SE = 1.014; t = -2.015; p = 0.045, Supplementary Material S3 ). 4 Discussion The aim of the present study was to investigate the associations between the RDoC PVS-, NVS-, CS-, and SP-domains and the mental burden of stress, anxiety, and depressive symptoms in a sample of university students.

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