A distinct tau oligomer strain defines the molecular and proteomic landscape of rapidly progressive Alzheimer's disease.

Acta Neuropathol · 2026 · PMC12999710 · PMID 41851356

Europe PMC DOI

hedged sentence

0.2700

closest p · 5.4× alpha

0.2700

boldest claim

The sentences

did not reach statistical significancep = 0.27not close (p > 0.1)

The decrease in metabolic activity was more pronounced for rpAD TauO, showing a trend toward greater toxicity compared with spAD TauO, although this difference did not reach statistical significance ( p = 0.27).

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