Combined ACEI and ARB therapy and ICU mortality in critically ill COVID-19 patients: a retrospective cohort study.

Front Pharmacol · 2026 · PMC12999808 · PMID 41868127

Europe PMC DOI

hedged sentence

0.0810

closest p · 1.6× alpha

0.0810

boldest claim

The sentences

did not reach statistical significancep = 0.081so close (0.05 < p ≤ 0.1)

ARB monotherapy demonstrated a modest negative association that did not reach statistical significance (p = 0.081), while ACEI monotherapy showed no meaningful effect ( Table 3 ).

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