Distinct immunologic patterns of response and resistance to anti-PD-1/PD-L1-based immunotherapy in patients with soft tissue sarcoma.

Front Immunol · 2026 · PMC12999908 · PMID 41869350

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did not reach statistical significanceno p-value reported

Only the proportion of TIM-3+ CD4+ memory conventional T cells was significantly higher in non-responders compared to responders (median 8.08% vs 20.30%, p=0.0240); proportion of TIM-3+ CD4+ memory regulatory T cells was also higher in non-responders, but differences did not reach statistical significance ( Figure 3B ).

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