Lactobacillus-Based Microbiome Therapy for Acne Vulgaris: A GRADE Systematic Review and Meta-Analysis of Randomized Controlled Trials.

J Cosmet Dermatol · 2026 · PMC13000680 · PMID 41853869

Europe PMC DOI

hedged sentence

0.1300

closest p · 2.6× alpha

0.1300

boldest claim

The sentences

did not reach statistical significancep = 0.13not close (p > 0.1)

The pooled MD favored probiotics numerically but did not reach statistical significance: MD = −9.07 (95% CI −20.71 to 2.57), p = 0.13.

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