Efficacy and safety of anti-VEGF/VEGFR monotherapy and combination with immune checkpoint inhibitors for advanced or metastatic renal cell carcinoma: a network meta-analysis.

BMC Cancer · 2026 · PMC13001274 · PMID 41559595

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a numerical trendno p-value reported

When compared to other intervention schemes, anlotinib showed a numerical trend toward a lower risk of hypertension; however, these pairwise comparisons did not reach statistical significance ( P > 0.05).

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did not reach statistical significanceno p-value reported

For the remaining interventions, pairwise comparisons with sunitinib did not reach statistical significance.

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