Electroacupuncture alleviates comorbid obesity and depression via the gut-brain axis: orchestrating SCFA-producing bacteria and hippocampal synaptic plasticity.

Consistent with the histological improvements, EA significantly lowered elevated serum levels of TG ( p < 0.05), although the reduction in TC did not reach statistical significance ( Figure 2C ).

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GO and KEGG enrichment analyses of these DEGs pointed to a highly significant involvement of the ‘MHC class II protein complex’ pathway and the ‘Neuroactive ligand-receptor interaction’ pathway ( Figures 6D , E ).

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