Comparison of Opioid Utilization in Older Adults with Rheumatoid Arthritis before and after Initiating Biological or Targeted Synthetic Disease-Modifying Antirheumatic Drugs.

Drugs Real World Outcomes · 2026 · PMC13003035 · PMID 41442071

Europe PMC DOI

hedged sentence

0.1100

closest p · 2.2× alpha

0.1100

boldest claim

The sentences

did not reach statistical significancep = 0.110not close (p > 0.1)

By contrast, while average opioid dose modestly decreased (22.29 [51.10] versus 21.59 [44.14]), this difference did not reach statistical significance ( p = 0.110).

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