Effectiveness and Safety of the Novel Selective Urate Reabsorption Inhibitor Dotinurad After Switching from Febuxostat in Patients with Stage B/C Heart Failure.

Drugs Real World Outcomes · 2026 · PMC13003072 · PMID 41307868

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

showed a trendp = 0.09so close (0.05 < p ≤ 0.1)

Serum uric acid levels showed a trend toward a reduction in Stage B (5.8 [4.4–6.3] to 5.3 [4.8–7.5] mg/dL, p = 0.09), whereas Stage C patients showed a significant increase (5.1 [4.6–6.6] to 5.4 [4.8–6.8] mg/dL, p = 0.02).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.