Barely Significant
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Biological Therapies for Urate Lowering and Inflammation Control in Gout Management.

J Inflamm Res · 2026 · PMC13003963 · PMID 41867470

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While the primary endpoint showed numerically higher response rates with SEL-212 compared to pegloticase during months 3 and 6 combined, this difference did not reach statistical significance. 22 However, percentage reductions in serum urate levels were statistically greater with SEL-212.

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